Misoprostol in dubai causes cervical ripening, dilation, cervical softening, uterine contractions.
Routes of administration
Oral route of administration
take Misoprostol pills with water Misoprostol takes 30 minutes to have effect.
buckle route of administration
Misoprostol tablets are placed between the gums and cheeks. they must be kept there approximately 30 minutes until they dissolve and then the remaining portions should be swallowed with water.
sublingual root of administration
Misoprostol tablets or abortion pills are placed under the tongue. they must be kept there approximately 30 minutes until they dissolve and then the remaining portions should be swallowed with water.
vaginal route of administration
Misoprostol tablets should be moistened with a saline solution and then introduced immediately in the vaginal cavity the patient should rest for 60 minutes.
Misoprostol is an exogenous prostaglandin. it acts on the myometrial cells in the uterus and it binds to prostaglandin receptors. Misoprostol causes an ATPase ca++ sequestering dependent on ca++ of the endoplasmic reticulum in the uterine smooth muscle that causes activation of myosin. which produces an increase in the frequency and intensity of uterine contractions.
the cervix consists of:
smooth muscle, connective tissue and collagen
Misoprostol causes cervical ripening dilation and softening. decreasing the amount of collagen fibers and allowing an increase in water molecules that intercalate among the collagen fibers and break them down. this is the result of increased contractions and cervical softening and dilation.
it causes cramps bleeding and expulsion of the products of conception. Misoprostol complements mifepristone’s action for complete expulsion of the products of conception.